A collaborative laboratory investigation of a problem in genomics, involving wet-lab generation of a large data set (usually finishing genomic sequence from a selected organism to high quality) and computer analysis of the data, annotating genes and repeat elements. In spring '07 the research problem will involve sequencing from D. mojavensis, and comparison with D. virilis and D. melanogaster to discern patterns of genome organization related to control of gene expression. Credit: 4 units; will satisfy the Biology Department laboratory requirement.  A Writing Intensive option is available (Bio  434W). Permission of the instructor required to enroll; please contact S. Elgin (selgin@biology.wustl.edu).