Online Syllabus

Date
Lecture

*BIO 493 students only (Exams)   ** BIO 4031 students only (Papers)

Read

HW
1/17

A brief history of time as a biological variable

1/19

Biological clocks, constant conditions, model systems

1

1/24

Entrainment Theory
Phase response curves

2
1/26

Introduction to class experiment (by Ms. Seol Hee Im)

3
1/31

...dawn to dusk and jet lag

2/2

A clock for all seasons

4
2/7

Physiology of Circadian Systems:
...in plants: light perception, pacemakers & outputs

5
2/9

...in molluscs: light perception, pacemakers, outputs

2/14

...in arthropods: light perception, pacemakers, outputs

6
2/16

...in birds & reptiles: light perception, pacemakers, outputs

7
2/21
*Exam I (Covers material through 2/14)
2/23

...in mammals: light perception pacemakers and outputs

8
2/28

...in mammals: multioscillators and single cell pacemakers

3/2

Analyses of periodic data; Enter experiment data in NSLC.

3/7
Cellular and Molecular Basis of Circadian Timing:
... in Drosophila and mammals: pacemakers
Experiment data due (Assignment #11)
9
3/9
...in mammals: light perception, pacemakers, and more outputs
(by Dr. Russ Van Gelder)
3/14
Spring Break
3/21

...in Drosophila: light perception & outputs (by Dr. Paul Taghert)
**Experiment outline due

11
3/23

...in fungi & plants: light perception, pacemakers, and more outputs

3/28

...in protists: light perception, pacemakers, and more outputs

3/30

Evolution of Circadian Clocks
**Experiment manuscript due

4/4

Clock uses:
…Adaptive Significance

4/6

Photoperiodism in plants and animals
**Review article outline due

4/11

...Sleep: from flies to people (by Dr. Paul Shaw)

4/13

…Endocrine rhythms (by Dr. Louis Muglia)

4/18
*Exam II (Covers material through 4/6)
4/20

Other Biological clocks:
...Tidal, lunar, circannual rhythms

4/25
When clocks break:
...Shift work, arrhythmia, dysrhythmia and depression
4/27

Clock repair:
...Chronotherapy and melatonin madness (Case studies)
**Review article due


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Washington University - Biology
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