Course Materials

Date

Lecturer

Topic
Readings
8/28 Chalker Organizational issues; Course overview; DNA structure and topology
  1. Roger D. Kornberg and Yahli Lorch
  2. Doug Brutlag
9/2 Chalker Chromatin
  1. Thomas Jenuwein and C. David Allis
9/4 Chalker Chromatin, nuclear organization, and epigenetics I
  1. Luis A. Parada and Tom Misteli
9/9 Chalker Chromatin, nuclear organization, and epigenetics II
  1. Luis A. Parada and Tom Misteli (see above)
9/11 Chalker Chromosome structure -- Telomeres
  1. Christopher W. Carroll and Aaron F. Straight
9/16 Chalker Chromosome structure -- Centromeres
  1. Wilhelm Palm and Titia de Lange
9/18 Majors Genes I: Promoters and Protein DNA interactions
  1. Kevin Struhl
  2. Chapter 1-A Primer .....
9/23 Majors Modular class II gene structure
9/25 Majors Transcriptional Activators: Structure and Analysis
9/30 Majors Mechanisms of Activation
10/2 Majors RNA pol I and III
10/7 1st In-Term Exam (11 lectures: 9/2 - 10/6)
10/9 Chalker DNA Replication
10/14 Chalker Epigenetic phenomena: PEV & X-chromosome inactivation
10/16 Chalker Epigenetic phenomena: Parental imprinting
10/17 Fall Break
10/21 Chalker DNA Repair & Recombination
10/23 Chalker DNA Repair & Recombination
10/28 Chalker DNA Rearrangements I
10/30 Chalker DNA Rearrangements II: Transposition
11/4 Majors RNA structure and processing I
11/6 Majors RNA processing II
11/11 Majors RNA; ribozymes and self-splicing
11/13 2nd In-term exam (10 lectures: 10/14-11/16)
11/18 Chalker Science in the era of “Genomics”
11/20 Chalker Genomics
11/25 Chalker Genomics
11/27 Thanksgiving Break
12/2 Chalker Genomics
12/4 Chalker Genomics
12/14 Final exam due by 5pm
Natural Sciences Learning Center
Washington University - Biology
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