Bio 3371cm

Date	Lecturer	Topic	Readings
8/28	Chalker	Organizational issues; Course overview; DNA structure and topology	Roger D. Kornberg and Yahli Lorch Doug Brutlag
9/2	Chalker	Chromatin
9/4	Chalker	Chromatin, nuclear organization, and epigenetics I
9/9	Chalker	Chromatin, nuclear organization, and epigenetics II
9/11	Chalker	Chromosome structure -- Telomeres
9/16	Chalker	Chromosome structure -- Centromeres
9/18	Majors	Genes I: Promoters and Protein DNA interactions
9/23	Majors	Modular class II gene structure
9/25	Majors	Transcriptional Activators: Structure and Analysis
9/30	Majors	Mechanisms of Activation
10/2	Majors	RNA pol I and III
10/7		1st In-Term Exam (11 lectures: 9/2 - 10/6)
10/9	Chalker	DNA Replication
10/14	Chalker	Epigenetic phenomena: PEV & X-chromosome inactivation
10/16	Chalker	Epigenetic phenomena: Parental imprinting
10/17		Fall Break
10/21	Chalker	DNA Repair & Recombination
10/23	Chalker	DNA Repair & Recombination
10/28	Chalker	DNA Rearrangements I
10/30	Chalker	DNA Rearrangements II: Transposition
11/4	Majors	RNA structure and processing I
11/6	Majors	RNA processing II
11/11	Majors	RNA; ribozymes and self-splicing
11/13		2nd In-term exam (10 lectures: 10/14-11/16)
11/18	Chalker	Science in the era of “Genomics”
11/20	Chalker	Genomics
11/25	Chalker	Genomics
11/27		Thanksgiving Break
12/2	Chalker	Genomics
12/4	Chalker	Genomics
12/14		Final exam due by 5pm