2004 HOWARD HUGHES FELLOWS

Fellows and Abstracts

  1. INVESTIGATIONS OF HETEROCHROMATIN PROTEIN 2 (HP2), AN ESSENTIAL COMPONENT OF HETEROCHROMATIN. Kwame Adu-Wusu, Gena Stephens, Sarah C. R. Elgin. Biology Department, Washington University, St. Louis, MO.
  2. EPIGENETIC VARIATION: CYTOSINE METHYLATION IN NATURAL VARIANTS OF ARABIDOPSIS THALIANA. Robert J. Carrasquillo, Hye Ryun Woo, Eric J. Richards (PI). Biology Department, Washington University, St. Louis, MO.
  3. CHARACTERIZATION OF MICE MODELS TO STUDY THE ROLE OF LRP IN ALZHEIMER'S DISEASE. Sarah Chen1, Guojun Bu2, Celina Zerbinatti2. Department of Biology, Washington University, St. Louis, MO1; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO2.
  4. ROLE OF PHOTORECEPTOR ACTIVITY IN THE DEVELOPMENT AND MATURATION OF THE ZEBRAFISH RETINA. Sheena Chew1, Eric H. Schroeter2, Rachel O. L. Wong2. Department of Biology, Washington University, St. Louis, MO.1. Department of Anatomy and Neurobiology, Washington University Medical School, St. Louis, MO.2
  5. INSERTIONAL MUTAGENESIS IN Danio rerio: TRANSPOSON-MEDIATED GENE TRAP SCREEN FOR LIVE MARKERS. Tien M. Chusak1, Stephen L. Johnson2. Biology Department, Washington University, St. Louis, MO1; Genetics Department, Washington University School of Medicine, St. Louis, MO2.
  6. THE ROLE OF ACTIVATED NOTCH IN CERVICAL CANCER. Amelia K. Clark1, Raphael Kopan2. Biology Department, Washington University, St. Louis, MO1; Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO.2
  7. FORMATION OF A LINEAR GRADIENT OF CHEMICAL MESSENGERS FOR USE WITH EXTERNAL CELLS. Michael DeWulf1, Yi Rao.2 Biology Department, Washington University, St. Louis, MO.1 Neurology Department, Washington University Medical School, St. Louis, MO.2
  8. MECHANISMS OF GLUCOSE TOXICITY: GENETIC SCREEN FOR ALTERED DEVELOPMENT RATES OF DROSOPHILA ON HIGH GLUCOSE MEDIUM. Andrew Elden1, Thomas J. Baranski2. Biology Department, Washington University, St. Louis, MO.1; Department of Molecular Biology and Pharmacology, Washington University Medical School, St. Louis, MO.2
  9. DEVELOPING A TRANSIENT EXPRESSION ASSAY FOR DROSOPHILA MELANOGASTER TESTES. Guillermo Gonzalez, Tatsuhiko Noguchi, Deborah Frank, Kathryn G. Miller. Biology Department, Washington University, St Louis, MO.
  10. TEMPORAL EVENTS ASSOCIATED WITH CELL DEATH IN MODELS OF PARKINSONISM. Rui Guan1, Karen O’Malley2.  Biology Department, Washington University, St. Louis, MO1; Department of Neurobiology and Anatomy, Washington University Medical School, St. Louis, MO.2
  11. NATIVE VS. INVASIVE SPECIES: IS ONE MORE POLLEN LIMITED THAN THE OTHER? Alexandra Harmon-Threatt, Jonathon Chase and Tiffany Knight. Biology Department, Washington University, St. Louis, MO.
  12. CEREBRAL ISCHEMIC TOLERANCE BY COBALT:  ROLE OF THE TRANSCRIPTION FACTOR HIF-2A AND NITRIC OXIDE. Casey Herrforth1;Yolanda Rangel2; Jeffery M. Gidday2. Biology Department, Washington University, St. Louis, MO1; Department of Neurosurgery, Washington University School of Medicine, St. Louis, MO.2
  13. CONSERVATION STRATEGIES INCORPORATING TIBETAN SACRED SITES OF DEQIN PREFECTURE, NORTHWEST YUNNAN. Kurt Hoffmeister1, Department of Biology, Washington University; Dr. Jan Salick2, Curator of Ethnobotany, Missouri Botanical Gardens, St. Louis, MO.
  14. Analysis of lia2 and its role in dna rearrangement in Tetrahymena Thermophila.  Rajat K. Jain, Douglas L. Chalker.  Biology Department, Washington University, St. Louis, MO.
  15. YEAST 2-HYBRID SCREEN TO IDENTIFY PROTEINS THAT INTERACT WITH SBDS. David X. Jin1, Amy S. Rawls and Daniel C. Link2.  Biology Department, Washington University, MO1; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO2.
  16. EPITHELIAL TO MYOFIBROBLAST TRANSITION IN THE LENS: ALTERNATIVE INTERACTIONS TO TGF-β IN THE FIBROSIS PATHWAY. Sharon Jin1, Claudia Garcia2, David C. Beebe. Biology Department, Washington University1, St. Louis, MO; Department of Ophthalmology, Washington University Medical School, St. Louis, MO2.
  17. TERRITORIAL BEHAVIOR AND HABITAT USE IN THREE PUERTO RICAN ANOLIS LIZARDS. Rebecca Kirby*, Michele A. Johnson, Su Wang, Jonathan B. Losos. Department of Biology, Washington University, St. Louis MO.
  18. QUANTATITIVE ANALYSIS OF CHANNELING IN GLYCOLYSIS IN INTACT E. COLI  Jia-an Koo, Georgia Shearer, Daniel Kohl. Biology Department, Washington University, St. Louis, MO.
  19. CHANNELING IN THE PATHWAYS OF GLUCOSE CATABOLISM IN INTACT MICROORGANISMS.  Jennifer Lee, Jia-an Koo, Georgia Shearer, Daniel H. Kohl.  Biology Department, Washington University, St. Louis, MO.
  20. STOICHIOMETRIC RELATIONSHIP BETWEEN FLOTILLIN-1 AND FLOTILLIN-2 IS REQUIRED FOR LYSOSOMAL LOCALIZATION.  Christin Lepus1, James Skinner2, Perry Bickel2.  Biology Department, Washington University, St. Louis, MO1; Departments of Medicine and of Cell Biology and Physiology, Washington University Medical School, St. Louis, MO2.
  21. INTEGRATION OF LUXCDABE TRANSPOSON IN SB300A1 SALMONELLA STRAIN FOR BIOLUMINESCENT TRACKING IN THE MOUSE GASTROINTESTINAL TRACT.  Felix Lui1, Jeffrey McKinney2. Biology Department, Washington University, St. Louis, MO1; Division of Infectious Diseases, Washington University Medical School, St. Louis, MO.2
  22. DETERMINANTS OF HEMOGLOBIN DEGRADATION BY THE PLASMEPSIN.  PROTEASES OF THE MALARIAL PARASITE.  Katherine I. Martin, Eva S. Istvan, and Daniel E. Goldberg.  Howard Hughes Medical Institute, Washington University, Departments of Molecular Microbiology and Internal Medicine, St. Louis, MO.
  23. PI(4,5)P2 BINDING TO ACTIN REGULATING PROTEINS.  Michelle McCully, David Sept.  Department of Biomedical Engineering, Center for Computational Biology, Washington University, St. Louis, MO.
  24. INVOLVEMENT OF EUKARYOTIC ELONGATION FACTOR (eEF) 1A-1 IN PALMITATE-INDUCED LIPOTOXICITY.  Emiko TA Morimoto1, Nica M Borradaile2, Jean E Schaffer2.  Biology Department, Washington University, St. Louis, MO1; Center for Cardiovascular Research, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO2.
  25. THE ROLE OF INSULIN SIGNALING IN THE BRAIN IN THE REGULATION OF BLOOD PRESSURE, SYMPATHETIC NERVOUS SYSTEM OUTPUT AND HYPOTHALMIC PITUITARY ADRENAL AXIS (HPA) DURING STRESS. Omobonike Oloruntoba1.  Simon J. Fisher2. Biology Department, Washington University, St. Louis, MO1; Metabolism and Internal Medicine Department, Washington University Medical School, St. Louis, MO2.
  26. CELL DIFFERENTIATION IN SIMPSON GOLABI BEHMEL SYNDROME. Palka Patel1, Beth Viviano2, Kathryn Mills2, Camila Pflederer2, Molly Kuhn2, Scott Saunders2.   Biology Department, Washington University, St. Louis, MO.1  Department of Pediatrics, Washington University School of Medicine. St. Louis, MO.2
  27. ZINC-FINGER TRANSCRIPTION FACTORS AS CANDIDATE GENES FOR HEREDITARY CATARACTS. Jevon Plunkett1, Thomas Bennett2, Alan Shiels2. Biology Department, Washington University, St. Louis, MO1.  Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 1.
  28. Biochemically Assessing the DNA Binding Properties of a Pseudomonas syringae TetR Family Protein Involved in Pathogen Virulence.  Justin Richner, Karen Preiter, and Barbara Kunkel.  Biology Department, Washington University, St. Louis, MO
  29. THE ROLE OF THE LOW-DENSITY LIPOPROTEIN RECEPTOR IN BRAIN APOLIPROTEIN E METABOLISM.  Colin Robinson1, David M. Holtzman, M.D.2, John D. Fryer2.  Biology Department, Washington University, St. Louis, MO1; Department of Neurology, Washington University, St. Louis, MO2.
  30. CLOCK AND BMAL1: A TRANSACTIVATION MECHANISM FOR CIRCADIAN GENES.  Victoria Rodriguez1, Vivek Kumar2, Joseph Takahashi2.  Biology Department, Washington University, St. Louis MO1; Howard Hughes Medical Institute, Department of Neurobiology and Physiology, Northwestern University, Evanston, IL2. 
  31. KINETICS AND THERMODYNAMICS OF THE FOLDING AND UNFOLDING OF THE JUN COILED COIL.  Kathleen Schwarz, D. André d’Avignon, Marilyn Emerson Holtzer, and Alfred Holtzer.  Chemistry Department, Washington University, St. Louis, MO.
  32. CIRCADIAN RHYTHMS IN ISOLATED NEURONS OF THE SUPRACHIASMATIC NUCLEUS. Nainesh Shah, Erik Herzog. Department of Biology, Washington University, St. Louis, MO.
  33. THE INTERACTION BETWEEN ENVIRONMENTAL AND SPATIAL FACTORS ON PATTERNS OF COMMUNITY ASSEMBLY IN ARTIFICIAL PONDS. Rachel S. Shulman, Jonathan M. Chase. Department of Biology, Washington University, St. Louis, MO.
  34. ROLES OF TRAF2 AND TRAF4 IN SIGNAL TRANSDUCTION PATHWAYS OF GITR.  Fine Song1, Edward M. Esparza2, Robert H. Arch2, Biology Department, Washington University, St. Louis, MO1; Departments of Internal Medicine and Pathology & Immunology, Washington University School of Medicine.2
  35. CHARACTERIZATION OF N-CADHERIN DEFICIENT OSTEOBLASTS IN MICE Joanna Urbanski1, Roberto Civitelli.2  Departments of Chemistry and Biomedical Engineering, Washington University, St. Louis, MO1.  Division of Bone and Mineral Diseases, Departments of Internal Medicine and Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO2.
  36. PERCEIVED FORAGING RISK IN WHITE-TAILED DEER: CAN GIVING-UP DENSITIES (GUDS) REVEAL A CORRELATION TO BOTH TICK ECTOPARASITISM AND CARNIVORE PRESENCE? Theodore Varns, Jonathan Chase, Brian Allan. Biology Department, Washington University, St. Louis, MO.
  37. DESIGNING A BALANCED LETHAL SELECTION SYSTEM FOR EXTERNAL GUIDE SEQUENCE PLASID MAINTENANCE IN SALMONELLA.  Jay-Ming Wang1 Yasmin Razia2 and Jeff McKinney2 Biology Department, Washington University, St. Louis, MO.1; Department of Pediatrics and Molecular Microbiology, Washington University, St. Louis, MO.2
  38. A SCREEN FOR ALDO-KETO REDUCTASE GENE DERIVATIVES IN DIABETIC IRIS TISSUE.  Shanelle Williams1, J. M. Petrash, Ph.D2. Biology Department, Washington Univeristy, St. Louis, MO1; Ophthalmology Department, Washington University Medical School, St. Louis, MO2.
  39. AFFECT OF LANDSCAPE ON FOOD WEB INTERACTIONS AND COMMUNITY COMPOSITION IN ARTIFICIAL TREE HOLES.  Crystal Yates-White1, Jamie Kneitel2, Jon Chase3.  Biology Department, Washington University, St. Louis, MO1; Department of Biological Sciences, California State University, Sacramento, CA2; Washington University, St. Louis, MO3